|
Darrera modificació: 2020-10-06
Bases de dades: Sciència.cat
Sabin, Susanna - Yeh, Hui-Yuan - Pluskowski, Aleks - Clamer, Christa - Mitchell, Piers D. - Bos, Kirsten I., "Estimating molecular preservation of the intestinal microbiome via metagenomic analyses of latrine sediments from two medieval cities", Philosophical Transactions of the Royal Society B, 375 (2020), publicació electrònica.
- Resum
- Ancient latrine sediments, which contain the concentrated collective biological waste of past whole human communities, have the potential to be excellent proxies for human gastrointestinal health on the population level. A rich body of literature explores their use to detect the presence of gut-associated eukaryotic parasites through microscopy, immunoassays, and genetics. Despite this interest, there is a lack of studies that have explored the whole genetic content of ancient latrine sediments through consideration not only of gut-associated parasites, but also of core community gut microbiome signals that remain from the group that used the latrine. Here, we present a metagenomic analysis of bulk sediment from medieval latrines in Riga (Latvia) and Jerusalem. Our analysis reveal survival of microbial DNA representative of intestinal flora as well as numerous parasites. These data are compared against parasite taxon identifications obtained via microscopy and ELISA techniques. Together these findings provide a first glimpse into the rich prokaryotic and eukaryotic intestinal flora of pre-industrial agricultural populations, which may give a better context for interpreting the health of modern microbiomes.
- Matèries
- Arqueologia
Medicina - Pesta i altres malalties
- URL
- https://www.academia.edu/44230905/Estimating_molecu ...
|